Selecting effective ammunition for big game hunting involves understanding how bullet construction, weight, and velocity influence performance on animals of different sizes and toughness levels. Each species presents unique challenges shaped by bone density, habitat type, and common shooting distances. Hunters rely on rounds that balance penetration with controlled expansion to achieve ethical harvests across varied environments. Careful attention to cartridge characteristics makes it easier to match specific animals with ammunition that delivers accuracy, dependable terminal performance, and consistent field results across both open and heavily timbered terrain.
White-Tailed Deer (Recommended: 5–7 Effective Cartridges)

White-tailed deer respond well to mid-caliber rounds that offer controlled expansion and manageable recoil, allowing accurate placement across mixed terrain. Cartridges such as the .243 Winchester, .270 Winchester, 6.5 Creedmoor, .308 Winchester, .30-30 Winchester, .260 Remington, and .25-06 Remington maintain enough energy for ethical penetration without excessive meat damage. Their balanced performance supports clean harvests in hardwood forests, brushy corridors, agricultural edges, and transitional habitats where deer frequently appear at varied distances.
Mule Deer (Recommended: 5–7 Effective Cartridges)

Mule deer occupy open basins and high desert plateaus where long-range shooting becomes common, requiring flat-trajectory rounds with strong retained energy. Popular options include the .270 Winchester, .280 Ackley Improved, 7mm Remington Magnum, .30-06 Springfield, 6.5 PRC, .308 Winchester, and .300 Winchester Magnum. Aerodynamic bullets help reduce wind drift and maintain accuracy at distance. These cartridges offer dependable penetration for larger-bodied mule deer encountered across sagebrush flats, canyon rims, foothill slopes, and high-country ridgelines.
Elk (Recommended: 4–6 Heavy Penetrating Cartridges)

Elk demand cartridges capable of deep penetration through dense muscle and heavy bone, especially at varied angles common in mountainous terrain. Proven choices include the .300 Winchester Magnum, .338 Winchester Magnum, .35 Whelen, 7mm Remington Magnum, .300 PRC, and .300 Weatherby Magnum. Bonded or monolithic bullets help ensure reliable expansion without fragmentation. Elk habitats include timbered canyons, alpine meadows, and steep transitional slopes, where high retained energy supports ethical and effective harvests.
Moose (Recommended: 4–6 Large-Caliber Cartridges)

Moose require large-caliber rounds with high sectional density to push significant momentum through thick hide, heavy bone, and deep muscle layers. Effective selections include the .338 Winchester Magnum, .375 H&H Magnum, .35 Whelen, .300 PRC, .300 Winchester Magnum, and .338 Lapua Magnum. These cartridges maintain structural integrity and deliver straight-line penetration needed for consistent internal damage. Moose habitats span marshlands, boreal forests, and river corridors where longer shots and tight angles both demand strong bullet construction.
Black Bear (Recommended: 4–6 Medium-to-Large Cartridges)

Black bears benefit from cartridges that combine strong penetration with controlled expansion capable of handling dense fur, thick fat layers, and substantial muscle. Suitable rounds include the .308 Winchester, .30-06 Springfield, .270 Winchester, .45-70 Government, 7mm Remington Magnum, and .35 Remington. Reinforced jackets and bonded cores help maintain bullet structure when encountering bone. These characteristics support clean harvests in rugged mountain slopes, dense berry thickets, and mixed-forest terrain where black bears commonly feed and travel.
Brown Bear (Recommended: 4–6 Very Heavy Cartridges)

Brown bears require exceptionally powerful ammunition capable of pushing through substantial mass with reliable penetration. Standard rounds include the .375 H&H Magnum, .416 Remington Magnum, .338 Winchester Magnum, .458 Winchester Magnum, .450 Marlin, and .404 Jeffery. Monolithic or premium bonded bullets ensure structural integrity during close-range encounters. Brown bears inhabit coastal river corridors, tundra margins, and dense brush where unpredictable engagements demand cartridges providing maximum stopping power and dependable terminal performance.
Caribou (Recommended: 4–6 Flat-Shooting Cartridges)

Caribou inhabit vast tundra regions where long, windy shots often occur across open terrain. Effective choices include the .270 Winchester, .30-06 Springfield, 7mm Remington Magnum, .308 Winchester, 6.5 Creedmoor, and .280 Ackley Improved. Aerodynamic bullet designs help counter crosswinds and maintain accuracy at extended ranges. Caribou have a lighter bone structure, allowing controlled-expansion bullets to perform efficiently without excessive recoil, especially during migrations across ridgelines and wide-open valleys.
Mountain Goat (Recommended: 4–6 High-BC Cartridges)

Mountain goats navigate steep, rocky landscapes where accurate long-range shooting becomes essential. Reliable rounds include the .270 Winchester, 7mm Remington Magnum, .280 Ackley Improved, 6.5 PRC, .30-06 Springfield, and .300 Winchester Magnum. Their lean bodies require bullets that expand reliably without causing excessive fragmentation on angled shots. High elevation and swirling alpine winds increase the importance of aerodynamic bullet profiles and consistent velocity for ethical results on sheer cliffs and talus fields.
Bighorn Sheep (Recommended: 4–6 Accurate Moderate-Recoil Cartridges)

Bighorn sheep favor rugged mountain habitats with long sightlines where precision becomes critical. Suitable choices include the .270 Winchester, 6.5 Creedmoor, .280 Ackley Improved, 7mm Remington Magnum, .30-06 Springfield, and .300 Winchester Magnum. Controlled-expansion bullets offer appropriate penetration for their lighter frames. High ballistic efficiency helps maintain accuracy across open basins, canyon walls, and windswept slopes where bighorn sheep often hold positions on narrow ledges or high ridgelines.
Pronghorn (Recommended: 4–6 Flat-Trajectory Cartridges)

Pronghorn require extremely flat-shooting rounds capable of countering steady prairie winds across wide-open terrain.Effective options include the .243 Winchester, .25-06 Remington, .257 Weatherby Magnum, 6.5 Creedmoor, .270 Winchester, and .22-250 Remington. Lightweight bullets maintain high velocity and reduce bullet drop at long distances. Their lighter bone structure allows efficient performance from controlled-expansion designs. These characteristics suit pronghorn behavior in vast grasslands, rolling plains, and sagebrush flats.
Wild Boar (Recommended: 5–7 Penetration-Focused Cartridges)

Wild boar present tough challenges due to their thick hide, resilient muscle, and formidable shoulder shields requiring strong penetration. Effective rounds include the .308 Winchester, .30-06 Springfield, .450 Bushmaster, .45-70 Government, .35 Whelen, .44 Magnum, and 7.62×39 with bonded or solid bullets. Close-range encounters in brushy thickets, agricultural fields, and rugged woodlands demand ammunition capable of breaking heavy bone while delivering steady expansion for ethical harvests.
Bison (Recommended: 4–5 Heavy Deep-Penetrating Cartridges)

Bison require extremely powerful rounds capable of penetrating deep into vital organs through heavy bone and dense muscle. Proven options include the .45-70 Government (modern high-pressure loads), .375 H&H Magnum, .338 Winchester Magnum, .450 Marlin, and .300 Winchester Magnum. Heavy, bonded bullets maintain momentum and structural integrity at moderate distances. These rounds suit the large size and muscular build of bison encountered on open prairies, river breaks, and historic range landscapes.
Mountain Lion (Recommended: 4–5 Accurate Light-to-Moderate Cartridges)

Mountain lions respond best to precise, moderate calibers offering clean penetration suited to their slender frames. Suitable rounds include the .243 Winchester, .257 Roberts, .25-06 Remington, .270 Winchester, and 6.5 Creedmoor. Encounters often occur in steep, rugged terrain where shot windows are brief. Controlled-expansion bullets deliver predictable performance without excessive force, making these cartridges ideal for fast, precise shooting scenarios in broken canyons and rocky timbered slopes.
Wolf (Recommended: 4–5 Precise Moderate-Recoil Cartridges)

Wolves require accurate, flat-shooting rounds with reliable expansion that match their agile movement and varied habitats. Effective choices include the .243 Winchester, .308 Winchester, .270 Winchester, 6.5 Creedmoor, and .22-250 Remington with appropriate bullet construction. Wolves travel quickly through forests, tundra, and open plains, making speed and precision crucial. Controlled-expansion bullets provide ethical penetration without excessive damage during fast-paced encounters across diverse North American landscapes.



